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Definition English:
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GPI-linked proteins consisting of eight elongated leucine-rich repeats at their N-temini that are connected to the GPI by a "stalk" region rich in prolines, serines and threonines. They bind to NOGO PROTEIN; however, some Nogo receptors also bind MYELIN ASSOCIATED GLYCOPROTEIN and other cell surface glycoproteins. Interactions between nogo receptors and their ligands modulate nerve growth and NEURONAL PLASTICITY. |